Saturday, April 26, 2008

Support The Stennis Foundation!

We need everyone in New Jersey to come out and support The Stennis Foundation on Saturday, May 17, 2008, when a "One Step Closer" Walk for Leukodystrophy will be held! If you've never attended a "One Step Closer" Walk, you are missing a blessing!

This walk will be at Lombardi Field, at Old Bridge High School. Late registration will begin at 12:00, the 4-mile Walk will begin at 1:00. Registration fee is $10 per person, which includes a t-shirt. Online registration is open at You can even pay your registration fee online, using PayPal.

Don't delay! Sign up today! Go right now!

After you have signed up, tell all your friends and family members to sign up. Then get other friends, family, neighbors and coworkers to sign up and to sponsor you -- so much per mile, or for a flat rate.

With your help, we will be "One Step Closer to a Cure" for the Leukodystrophies! Please help us bring these diseases DOWN!

Here's the video from the Walk we had in Allen, Texas.

And here is a general information video, regarding The Stennis Foundation.

Thank you for supporting The Stennis Foundation!

Thursday, April 17, 2008

Aldagen Announces Initiation of ALD-101 Phase III Trial

Aldagen Announces Initiation of ALD-101 Phase III Trial for Improving Cord Blood Transplants in Pediatric Patients With Inherited Metabolic Diseases
Trial to Be Conducted at Multiple Clinical Sites

DURHAM, NC--(Marketwire - April 16, 2008) - Aldagen, Inc. today announced that the first patient has been treated in a Phase III clinical trial for ALD-101. Aldagen is developing ALD-101 to improve cord blood transplants used to treat inherited metabolic diseases in pediatric patients. ALD-101 is a population of adult stem cells isolated from cord blood using Aldagen's proprietary technology. The company commenced the Phase III clinical trial of ALD-101 to evaluate its ability to accelerate neutrophil and platelet engraftment following cord blood transplantation in these patients.

40 pediatric patients with inherited metabolic diseases undergoing a cord blood transplant will be treated in the multi-site Phase III clinical study. The primary goal of the study is to determine if ALD-101 can accelerate the restoration of circulating platelets. A 24-patient Phase I/II study of ALD-101 was previously conducted and a statistically significant reduction in the time to platelet engraftment was observed in patients receiving ALD-101 as part of a cord blood transplant compared to patients who had received a cord blood transplant without ALD-101 in an earlier independent clinical trial.

Cord blood transplantation has been shown to successfully treat children with inherited metabolic diseases, such as Krabbe Syndrome, Metachromatic Leukodystrophy, Hurler Syndrome, and Adrenoleukodystrophy. These diseases are often fatal with few treatment options other than a stem cell transplant. Cord blood transplants do carry numerous risks. The time for cord blood transplant patients to regain adequate levels of neutrophils and platelets, referred to as engraftment, can be lengthy. During the period of time between transplant and engraftment, patients are at high risk for life-threatening infections, bleeding, and transfusion-related reactions.

About Cord Blood Transplants

Umbilical cord (UBC) stem cells are located in the umbilical cord of a newborn at birth. After the baby has been delivered and the umbilical cord has been cut, blood is drawn from the umbilical cord. It is a completely non-invasive procedure with absolutely no risk to either mother or child. Umbilical cord stem cells are not embryonic stem cells.

About Aldagen, Inc.

ALDAGEN is a biopharmaceutical company developing proprietary regenerative cell therapies that target significant unmet medical needs. The Company has four product candidates in clinical trials. Aldagen's most advanced product candidate, ALD-101, is currently in a pivotal Phase III clinical trial to evaluate its effectiveness in improving cord blood transplants used to treat inherited metabolic diseases in pediatric patients. The Company is also conducting Phase I/II clinical trials on three product candidates: ALD 151 to improve cord blood transplants in the treatment of leukemias, ALD-301 to treat critical limb ischemia, and ALD-201 to treat ischemic heart failure. Aldagen's product candidates consist of specific populations of active adult stem cells that the Company isolates using its proprietary technology. To learn more about ALDAGEN, please visit

For more information, contact:
Ed Field
President and COO

Michelle Linn
Linnden Communications

Wednesday, April 16, 2008

Upcoming "One Step Closer" Walk for Leukodystrophy in Old Bridge, NJ

Wanted to let you know about this opportunity to rally the troops and kick some Leukodystrophy butt! :)

Susannah Rutan is putting together a "One Step Closer" Walk in Old Bridge, NJ, to raise funds for The Stennis Foundation. She is a nanny for a boy named Eric Brown, age 9, who has an unnamed Leukodystrophy.

The Walk will be Saturday, May 17, at Lombardi Field at the High School in Old Bridge. Check-in begins at 12:00, the Walk begins at 1:00. Registration fee is $10 which includes a t-shirt.

Online registration is now open at

I really hope you will mark your calendars, save the date, and be at the Walk. I will be there -- and I want to see you!!

p.s. If you have friends and/or businesses that would be willing to help sponsor the Walk, that would be awesome!

p.s.p.s. Pleeeeeeeeeeeeeeeease repost this, and help spread the word! If you have websites, such as MySpace, Facebook, CaringBridge, or other personal sites, please post this information on your site. Also, please copy and paste this into an email, and send it to everyone you know.

We really need a good turnout and need to raise funds for desperately needed research! Please help us!!